Endocrine Abstracts

Introduction: Oncogenic Osteomalacia (OO) is a rare paraneoplastic syndrome, resulting from fibroblast growth factor 23 overproduction. The rarity of the disease and nonspecific symptoms often cause delay in diagnosis by months, or even years. There are two cornerstones in the diagnostic process. The first concerns clinical identification, where awareness of this uncommon ailment combined with hypophosphatemia and clinical signs may be sufficient to identify OO. The second inv...

IntroductionTumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused mainly by a phosphaturic mesenchymal tumour (PMT) as a consequence of fibroblast growth factor 23 (FGF23) overproduction. The manifestation of TIO is mostly musculoskeletal. Locating the PMT is usually challenging and a successful surgical resection of the tumour leads to complete recovery.Case presentationA 42-year-old, Ca...